Labelling of plasma proteins with radioactive iodine
نویسندگان
چکیده
منابع مشابه
Standardization of Radioactive Iodine.
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It is now thirteen years since Hertz and Roberts (1942) introduced radioactive iodine in the treatment of thyrotoxicosis, and in the succeeding years it has increasingly established itself in the therapy of this condition and has been widely used in the United States of America. We have previously recorded our experience in this country in a small series of cases (Blomfield et al., 1951, 1953; ...
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The labelling of proteins by the iodine monochloride method was studied by using a mathematical model. The equations used were primarily derived from the mass law equation of the isotopic exchange reaction between [(125)I]iodide and iodine monochloride. For convenient application, all equations were programmed into a computing desk-top calculator. To support the validity of the theoretical mode...
متن کاملRadioactive Iodine as an Indicator of the Metabolism of Iodine
According to Harington, two fractions, one “thyroxine-like” and the other “diiodotyrosine-like,” can account for all of the organic iodine found in the thyroid gland (1). The metabolism of these compounds has been reviewed recently by Salter (2). The labeling of iodine by radioactivity provides for the first time a desirable tool for the study of the endogenous or normal rates of formation of t...
متن کاملRadioactive Iodine as an Indicator of the Metabolism of Iodine
The early discovery that physiological activity’in the thyroid gland was associated with an iodoprotein (1, 2) led logically to investigations of the physiological effects and chemical properties of various proteins or protein fractions that had been subjected to artificial iodination. In 193334, Abelin et al. observed physiological effects resembling those produced by the thyroid gland after t...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1956
ISSN: 0306-3283
DOI: 10.1042/bj0620135